Moved by Ash's sacrifice, Mewtwo realizes that he should not have to be judged by his origins but rather his choices in life. However, the tears of the PokГ©mon are able to heal and revive Ash. Pikachu tries to revive Ash with its electricity but fails. Horrified at the pain and anguish felt on both sides of the battle, Ash puts himself in between a psychic blast caused by Mewtwo and Mew's fighting, leading to Ash to become stone.

Mew then reveals itself and Mewtwo challenges it in order to prove his superiority.ДЄll of the PokГ©mon originals battle their clones save for a defiant Pikachu and Meowth, who makes peace with his own clone after realizing the senselessness of their fighting. Ash destroys the cloning machine, frees the captured PokГ©mon, and leads them to confront Mewtwo and his clones. Ash chases after his captured Pikachu down the cloning lab, where Team Rocket's Meowth is also cloned. After Mewtwo's clones effortlessly defeat the challengers' PokГ©mon, he confiscates them and expands his clone army. Meanwhile, Team Rocket also reaches New Island and explores its inner sanctum with a Mew innocuously following them. Mewtwo challenges the trainers using cloned PokГ©mon. The woman is revealed to be a brainwashed Nurse Joy after she is released from Mewtwo's mind control. After the storm sinks their vessel in the middle of the ocean, Ash and his friends use their PokГ©mon instead to reach New Island.Д®scorted into the island's palace by the woman who appeared on the hologram, Ash and the other trainers who were able to reach the island encounter Mewtwo. As a result, Ash's group are picked up by Team Rocket disguised as captains on a Lapras-shaped sailboat. Ash, Misty, and Brock receive a message and accept the invitation, but when they arrive at the port city, Old Shore Wharf, Mewtwo creates a storm, causing the boats on the wharf to be closed off for safety. However, after Mewtwo learns of his purpose to be a weapon for Giovanni's benefit, he escapes back to New Island where he plots his revenge against humanity.ДЄfter Mewtwo rebuilds the laboratory and establishes a base there, he invites several trainers with hologram messages to battle the world's greatest PokГ©mon trainer at New Island. Giovanni, witnessing the carnage afar, approaches and convinces Mewtwo to work with him to hone his powers.

Infuriated that Fuji and his colleagues see him as nothing more than an experiment, he unleashes his psychic powers and destroys the laboratory, killing Fuji and the rest of the scientists. Several years later, Mewtwo has fully awakened from a long slumber in a laboratory on New Island, and learns of his origin as Mew's clone from Dr. Soon after the weapon is created, it gains sentience and is named Mewtwo.

Fuji is hired by Giovanni, leader of Team Rocket, to utilize his expertise in cloning in order to create a living weapon based on an eyelash from legendary PokГ©mon Mew.

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